Brief Report: Erythrocytosis Associated with Hepatocellular Carcinoma

Erythrocytosis associated with hepatocellular carcinoma.

I N A PREVIOUS STUDY, it was shown that erythrocytosis was present in 11.7 per cent of southern Chinese patients with hepatocellular carcinoma but that the mechanism of production remained obscure.’ Plasma erythropoiesis-stimulating factor ( ESF ), assayed on the fasted rat, was not increased in four subjects studied. Subsequent reports of the existence of erythrocytosis in hepatocellular carci...

A possible mechanism for the erythrocytosis associated with hepatocellular carcinoma in man.

these pathological states, elevated levels of erythropoietin (ESF) have been detected in the serum, plasma, or urine, and in the affected tissues or encvsted fluid. Such observations have led to the speculation that increased production of the ESF by the tumor tissue may be responsible for the development of the accompanying erythrocytosis. In attempting to determine the mechanism underlying th...

Brief report A novel mutation in the erythropoietin receptor gene is associated with familial erythrocytosis

Primary familial erythrocytosis (familial polycythemia) is a rare myeloproliferative disorder with an autosomal dominant mode of inheritance. We studied a new kindred with autosomal dominantly inherited familial erythrocytosis. The molecular basis for the observed phenotype of isolated erythrocytosis is heterozygosity for a novel nonsense mutation affecting codon 399 in exon 8 of the erythropoi...

Clear Cell Hepatocellular Carcinoma with Associated Tuberculosis-A Case Report

Clear cell hepatocellular carcinoma (CCHCC) is a rare variant of classical hepatocellular carcinoma (CHCC). Most of these cases pose a histological diagnostic dilemma with broad range of differentials of tumor with clear cell morphology. Use of immunostains or presence of classical hepatocellular carcinoma morphology focally aids in accurate diagnosis of these lesions. We report a case of a 62-...

Hepatocellular Carcinoma in Sheep